High Skin Hydration and Comfortable Texture of a Moisturizing Lotion Fulfilled by Controlling the Phase Sequence of a Vesicle/Micelle Complex

Kei Watanabe, M. Nishida, Kanako Nishimura, Yoriko Mune, Yuji Matsushita, Ayano Nakamura, K. Tsuchiya, H. Sakai, H. Hoffmann
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引用次数: 3

Abstract

The formation of micellar solutions with hydrophilic surfactants is generally used to include oily substances into transparent water-based formulae. However, a restriction exists on hydrophilic surfactants due to their sticky feeling arising from long hydrophilic groups. We found a stable transparent dispersion of a lipophilic polyether-modified silicone ( PEMS ) in combination with an ionic surfactant by a certain procedure. Various analyses revealed that it is a 10 ─ 100 nm sized vesicle / micelle complex consisting of bi-molecular membranes. Although there are several reports on the vesicle formation of PEMS, the practical stability has been insufficient because of the high fluidity of the membrane. The present vesicle / micelle complex can solubilize silicone oils, which have been considered difficult, resulting in a feature of good spreadability onto sur-faces. In addition to that, it shows a non-sticky, highly permeable feeling owing to the formation of a lamellar liquid crystalline phase by a water evaporation on application despite the high glycerol concentration. The present moisturizing lotion fulfilled mutually exclusive events of high skin hydration to prepare for future skincare items : a moisturizing lotion with an important func-tion and a highly comfortable texture.
通过控制囊泡/胶束复合物的相序实现高皮肤水合性和舒适质地的保湿乳液
与亲水性表面活性剂形成胶束溶液通常用于将油性物质纳入透明水基配方中。然而,亲水性表面活性剂由于其长亲水性基团产生的粘性而受到限制。我们通过一定的程序发现了一种稳定的亲脂聚醚改性有机硅(PEMS)与离子表面活性剂的透明分散体。各种分析表明,它是由双分子膜组成的10 ~ 100 nm大小的囊泡/胶束复合物。虽然有一些关于PEMS囊泡形成的报道,但由于膜的高流动性,其实际稳定性不足。所制备的囊泡/胶束复合物可以溶解硅油,从而使硅油具有良好的表面涂抹性。除此之外,尽管甘油浓度很高,但由于在应用时水蒸发形成了层状液晶相,因此它显示出一种不粘性,高度渗透性的感觉。目前的保湿乳液满足了高度皮肤水合作用的相互排斥的事件,为未来的护肤项目做准备:一种具有重要功能和高度舒适质地的保湿乳液。
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