A Cost-Efficient Design for Microarray Image System

Abstract

Image based Microarray processing has been widely applied to the biotechnology field for identifying SNP variations. In order to reduce the cost for manufacturers, a flexible design for handling different layouts of containers and different numbers of spots is necessary to accomplish the need for different throughputs on the same microarray instrument. The key to making the microarray technology successful is spot recognition during the image processing. There are many factors that could affect the quality and alignment of spots. Both high accuracy and automation in spot intensity acquisition is required to have a correct result. Here, we present a cost-efficient design that will accommodate for different spot layouts with minimal required information.