Vascular compliance in hypertension

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Pub Date : 1988-11-01 DOI:10.1109/IEMBS.1988.94497

Stanley M. Finkelstein, W. Feske, J. Mock, P. Carlyle, Tom S. Rector, Spencer H. Kubo, Jay N. Cohn

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引用次数: 9

Abstract

Pulse contour analysis was used to determine systemic arterial vascular compliance in hypertensive (HT) and normotensive (NT) subjects. In seven hypertensives aged 43-58 yrs (mean age 52.1+or-5.5 yrs) and seven normotensives aged 33-59 yrs (mean age 43.7+or-9.9 yrs) both large artery (C1) and distal arterial (C2) compliance were determined from a peripheral arterial pressure waveform and cardiac output. Age differences were not statistically significant. Mean arterial pressure was 29% higher in HT (p<0.001). Cardiac output was 12% higher and heart rate was 6% lower in HT, but these differences were not significant. Systemic vascular resistance was 17% higher in HT (NS), while proximal and distal arterial compliance were 15% and 70% lower, respectively, in HT compared to NT. Only the difference in C2 was significant (p<0.02). Thus, distal vascular compliance may be a clinically useful parameter for evaluating hypertensive subjects before and during therapeutic intervention.<>

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高血压的血管顺应性

脉搏轮廓分析用于确定高血压(HT)和正常血压(NT)受试者的全身动脉血管顺应性。在7例43-58岁的高血压患者(平均年龄52.1±5.5岁)和7例33-59岁的血压正常者(平均年龄43.7±9.9岁)中，我们通过外周动脉压波形和心输出量来确定大动脉(C1)和远端动脉(C2)的顺应性。年龄差异无统计学意义。HT组平均动脉压升高29% (p>

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Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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