A clinical study of optical coherence tomography and fundus fluorescein angiography findings in central serous chorioretinopathy with co-relation to visual outcome in a tertiary care center of North-East India

Abstract

Purpose: The purpose is to identify the characteristic findings of central serous chorio-retinopathy (CSCR) on fundus fluorescein angiography (FFA) and optical coherence tomography (OCT) in a tertiary care center of North-East India and to clinically correlate the final visual outcome with OCT values at the end of 6 months' follow-up. Methodology: A total of 70 cases (77 eyes) of CSCR were taken up for this prospective observational study. Other pathological causes of macular edema were excluded from the study. Visual acuity, OCT, and FFA were done in all cases at day 1 and were followed up till 6 months. OCT was done at each visit. Results: The mean age of the patient was 40 years (range 20–59 years, standard deviation [SD] 11.98). The day 1 mean vision was 0.72 logarithm of the minimum angle of resolution (log MAR), SD 0.30, P < 0.0001. The final mean vision at 6 months reduced to 0.22 Log MAR (SD = 0.1116 and P < 0.0001). The mean foveal thickness and macular volume (MV) was found to be 467.27 μm (SD 172.11) and 9.86 mm3 (SD 2.52), respectively, at day 1 of presentation, which reduced to 203.92 μm (SD 40.90; P = 0.0156) and 6.71 mm3 (SD 0.71; P = 0.0009, paired t-test) at the end of 6 months. Conclusion: Although the maximum visual recovery was attained at the 3rd month, cases with higher MV and foveal thickness at day 1 had poor final visual acuity. OCT alone can be helpful in determining the final visual outcome and the need for early therapy.