Reporting on Adverse Clinical Events

J. Dill
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Abstract

Consequences related to Sophora secundiflora intentional abuse or intentional misuse were evaluated using data from 47 reports received by the Texas Poison Center Network during 2000 to 2018. The part of Sophora secundiflora most frequently involved in the ingestion was the seed (91.5%). Relatively few cases reported the ingestion of the flower (2.1%) or an unknown plant part (6.4%). Of the seed ingestion cases, the mean number of sees ingested was 1.7 (range =1-16 seeds) with the majority involving the ingestion of only one seed (82.9%). Fewer reports involved 2 seeds (11.4%), 6 seeds (2.9%), and 16 seeds (2.9%). Almost half of the patients (48.9%) were 13 to 19 years of age. Approximately one fifth (21.3%) were aged 12 years or less, and approximately one third (29.8%) were at least 20 years of age. The majority of patients were male (78.7%). The most frequently cited locations were the home (66%), school (17%), and public area (10.6%). Approximately one fifth were referred to a health care facility (19.1%). Slightly more than half (55.3%) of the cases reported symptoms, with the most frequently reported clinical effects including vomiting (34.0%), nausea (29.8%), and abdominal pain (21.3%). Based on this retrospective review of data from the Texas Poison Center Network, the authors concluded that approximately half of the cases of ingestion of Sophora secundiflora resulted in symptoms, predominantly gastrointestinal in nature. Sophora secundiflora [Sophora secundiflora, Texas Mountain Laurel] Forrester MB et al (MB Forrester, Independent Researcher, Austin, TX; e-mail: mathias.forrester@gmail.com) Abuse and misuse of Sophora secundiflora in Texas. Clin Toxicol (Phila) 58:302–303 (Apr) 2020
不良临床事件报告
使用2000年至2018年期间德克萨斯州毒物中心网络收到的47份报告中的数据,评估了与槐属二次双花故意滥用或故意误用有关的后果。次生苦参的食入部位主要为种子(91.5%)。相对较少的病例报告摄入花(2.1%)或未知的植物部分(6.4%)。食子病例中,平均食子数为1.7粒(范围为1 ~ 16粒),以单粒食子为主(82.9%)。2粒(11.4%)、6粒(2.9%)和16粒(2.9%)的报道较少。几乎一半的患者(48.9%)年龄在13 - 19岁之间。大约五分之一(21.3%)的患者年龄在12岁以下,大约三分之一(29.8%)的患者年龄在20岁以上。以男性居多(78.7%)。最常被提及的地点是家(66%)、学校(17%)和公共场所(10.6%)。约五分之一(19.1%)被转诊到卫生保健机构。略多于一半(55.3%)的病例报告了症状,最常见的临床症状包括呕吐(34.0%)、恶心(29.8%)和腹痛(21.3%)。基于对德克萨斯中毒中心网络数据的回顾性分析,作者得出结论,大约一半的食用槐属植物的病例导致症状,主要是胃肠道症状。Sophora secundiflora [Sophora secundiflora, Texas Mountain Laurel] Forrester MB等人(MB Forrester,独立研究员,Austin, Texas;电子邮件:mathias.forrester@gmail.com)在德克萨斯州的Sophora secundiflora滥用和误用。临床毒物杂志(费城)58:302-303(四月)2020
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