Current Treatment Strategies of COVID-19

Özge Aydın Güçlü, A. Görek Dilektaşlı
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Abstract

On 31 December 2019, the Wuhan Municipal Committee of Health and Healthcare (Hubei Province, China) reported that there were 27 cases of pneumonia of unknown origin with symptoms starting on the 8 December. On 7 January 2020, the Chinese authorities identified that the agent causing the outbreak was a new type of virus of the Coronaviridae family, temporarily called 'new coronavirus, 2019-nCoV'. On January 30th, 2020, the World Health Organisation (WHO) declared the outbreak an international emergency and described it as a pandemic in March 2020. While it was previously referred to as 2019-nCoV by WHO, on February 11, 2020, the disease was named as severe acute respiratory syndrome-coronavirus2. The disease was confirmed to have reached Turkey on 11 March 2020, after a patient who had returned to Turkey from Europe, tested positive. The most appropriate treatment approach to treating COVID-19 remains unclear. Current treatment protocols are based on limited data and are evolving rapidly as clinical data emerge. A large volume of data and publications from randomized controlled trials, observational cohorts, and case series are emerging promptly, some in peer-reviewed journals, others as manuscripts that have not yet been peer reviewed. The Republic of Turkey Ministry of Health invited the specialties societies to prepare a clinical protocol for the management of COVID-19. The Turkish Pandemic Working Group prepare the present recommendations with the evidence available at the time of preparing them. It is aimed to summarize the treatment management of COVID-19 in line with the current treatment recommendations in national and international guidelines. Keywords: COVID-19;pandemic;treatment.
当前COVID-19的治疗策略
2019年12月31日,中国湖北省武汉市卫生健康委员会报告,有27例原因不明的肺炎病例,症状始于12月8日。2020年1月7日,中国当局确定导致此次疫情的病原体是冠状病毒科的一种新型病毒,暂时称为“新型冠状病毒,2019-nCoV”。2020年1月30日,世界卫生组织(世卫组织)宣布此次疫情为国际紧急情况,并于2020年3月将其描述为大流行。虽然世卫组织之前将其称为2019-nCoV,但在2020年2月11日,该疾病被命名为严重急性呼吸综合征-冠状病毒2。在一名从欧洲返回土耳其的患者检测呈阳性后,该疾病于2020年3月11日被证实传到土耳其。目前尚不清楚治疗COVID-19的最适当治疗方法。目前的治疗方案是基于有限的数据,并随着临床数据的出现而迅速发展。来自随机对照试验、观察性队列和病例系列的大量数据和出版物正在迅速涌现,其中一些发表在同行评议的期刊上,另一些则是尚未经过同行评议的手稿。土耳其共和国卫生部邀请各专科学会编写COVID-19管理临床方案。土耳其大流行病工作组根据编写这些建议时所掌握的证据编写了这些建议。其目的是根据当前国家和国际指南中的治疗建议,总结COVID-19的治疗管理。关键词:COVID-19;疫情;治疗。
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