Endoscopic Pulsed Radiofrequency Ablation of Genicular Nerves for the Treatment of Chronic Knee Pain

Dipan C. Patel
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Abstract

Chronic knee pain is the second most common cause of chronic pain in the United States. Occasionally, patients become refractory to conventional treatments such as intraarticular cortisone injections and viscosupplementation. Patients who have exhausted these therapies or have a contraindication to the therapies may be candidates for diagnostic genicular nerve block and if successful, subsequent radiofrequency ablation (RFA). For patients who have undergone image-guided genicular nerve radiofrequency ablation with fluoroscopic or ultrasound guidance without success, an endoscopic approach can be used as an alternative modality with success. With direct visualization of the genicular nerves, the likelihood of success with an endoscopic approach increases as some patients can have varying anatomy of the genicular nerves for which cannot always be detected with fluoroscopy or ultrasound. The purpose of this study is to demonstrate the utilization of a direct endoscopic approach for genicular nerve RFA for patients with chronic knee pain that have failed to improve after image-guided genicular RFA with fluoroscopic or ultrasound guidance. Two patients who had underwent successful diagnostic genicular nerve blocks were assessed for pre-procedure and post-procedure visual analog scale (VAS) scores following endoscopic genicular nerve RFA after failure of the conventional image guided approach at 6 and 12 months. Both patients reported greater than 80% reduction in VAS score and improvement in function at 6 and 12 months Limitations of the current study is a limited number of patients, and lack of the use of a formal functional scale to demonstrate improvement. Ultimately, the conclusion was drawn that an endoscopically-guided genicular nerve RFA can be utilized successfully due to direct visualization of the genicular nerves when conventional approaches with Fluoroscopic/ultrasound guidance has failed to achieve analgesia and functional improvement. Key words: Genicular nerve block, endoscopic, radiofrequency ablation. knee pain, chronic osteoarthritis, genicular neuritis, genicular neuralgia, total knee arthroplasty, arthritis
内窥镜脉冲射频消融膝关节神经治疗慢性膝关节疼痛
在美国,慢性膝关节疼痛是慢性疼痛的第二大常见原因。偶尔,患者对关节内可的松注射和粘剂补充等常规治疗变得难治性。已经用尽这些治疗方法或对这些治疗有禁忌症的患者可以考虑诊断性膝神经阻滞,如果成功,随后进行射频消融术(RFA)。对于在透视或超声引导下行图像引导下膝神经射频消融术但未成功的患者,内镜下入路可作为一种成功的替代方式。通过直接观察膝神经,内窥镜方法成功的可能性增加,因为一些患者的膝神经解剖结构不同,不能总是用透视或超声检查到。本研究的目的是证明直接内窥镜入路治疗膝神经RFA对慢性疼痛患者的应用,这些患者在超声引导下无法改善图像引导下的膝神经RFA。两名成功诊断膝神经阻滞的患者在常规图像引导入路失败后的6个月和12个月对内窥镜膝神经RFA术前和术后视觉模拟评分(VAS)进行评估。两名患者在6个月和12个月时均报告VAS评分降低80%以上,功能改善。当前研究的局限性是患者数量有限,并且缺乏使用正式的功能量表来证明改善。最后,我们得出的结论是,当常规的透视/超声引导下的方法无法达到镇痛和功能改善时,内镜引导下的膝神经RFA可以成功地应用,因为它可以直接看到膝神经。关键词:膝神经阻滞,内镜,射频消融。膝关节疼痛,慢性骨关节炎,膝神经炎,膝神经痛,全膝关节置换术,关节炎
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