Intervention Strategies to Mitigate Psychosocial Challenges and Improve the Quality of Life of MDR-TB Patients - An Evaluation Study

E. Thiruvalluvan, S. Sellappan, Basilea Watson, M. Muniyandi
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Abstract

Introduction: The psychosocial well-being and treatment outcome in MDR-TB is far undesirable as the treatment is characterized by a rigorous treatment regimen for a long duration, adverse side effects, lower cure rate, and high treatment costs. This study aimed to devise an intervention strategy and test its feasibility and effectiveness to ensure the patients’ quality of life (QOL) and to promote adherence. Methodology: The study population included all MDR-TB patients, of age 18 years and above registered in 16 tuberculosis units (TUs) under Chennai Corporation for treatment during the year 2014. Researchers have devised an intervention strategy package that included motivational interview (MI) module, counseling support as well as nutritional support. Participants were included in the study after getting informed consent. Motivational interviewing was offered at five times during the study period. Each participant received minimum 15 individual counselling sessions. All participants but two received nutritional flour packet weighing half kilogram every month. Results: Of 35 participants enrolled in the study, one third was women. Poor QOL was experienced by 19 participants out of 35 at the start of treatment that came down to 2 after the study. QOL scores in all four domains were significantly high and depression level score was significantly lowered at the end of the treatment. At the start of the treatment twenty, four out of thirty-five participants were dissatisfied with their health that came down to five at the end of treatment. Conclusion: Intervention strategy not only had a great impact on the QOL of study participants but also contributed to better treatment adherence and desirable treatment outcome. Therefore, researchers emphasize the need to adopt this Intervention Strategy through the provision of trained, professional MDR-TB counsellors. Further, larger studies of multi-state/ multi-site may be taken up to standardize the intervention strategies adopted in this study.
减轻耐多药结核病患者心理挑战和改善生活质量的干预策略-一项评估研究
引言:耐多药结核病的心理社会健康和治疗结果非常不理想,因为这种治疗的特点是长期严格的治疗方案、不良副作用、治愈率较低和治疗费用高。本研究旨在设计干预策略,并检验其可行性和有效性,以确保患者的生活质量(QOL)和提高依从性。方法:研究人群包括2014年在金奈公司16个结核病单位(TUs)登记治疗的所有18岁及以上耐多药结核病患者。研究人员设计了一套干预策略,包括动机访谈(MI)模块、咨询支持以及营养支持。参与者在获得知情同意后被纳入研究。在研究期间进行了五次动机性访谈。每位参与者至少接受了15次个别辅导。除两人外,所有参与者每月都收到半公斤重的营养面粉包。结果:参加研究的35名参与者中,三分之一是女性。35名参与者中有19人在治疗开始时经历了较差的生活质量,研究结束后降至2人。治疗结束时,四个领域的生活质量评分均显著较高,抑郁水平评分显著降低。在治疗开始时,35名参与者中有24人对自己的健康不满意,在治疗结束时下降到5人。结论:干预策略不仅对研究对象的生活质量有较大影响,而且有助于提高治疗依从性和治疗效果。因此,研究人员强调需要通过提供训练有素的专业耐多药结核病咨询师来采用这一干预策略。进一步,可以进行更大规模的多状态/多地点研究,以规范本研究中采用的干预策略。
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