SYNTHESIS AND PROPERTIES OF NANODISPERSED LUMINESCENT STRUCTURES BASED ON LANTHANUM FLUORIDE FOR OPTOPHARMACOLOGY AND PHOTODYNAMIC THERAPY

Abstract

Nanocrystalline lanthanum fluoride of hexagonal syngonium and terbium-activated lanthanum fluoride were synthesized. The structural characteristics of the synthesized samples were investigated by XRD, TEM, FTIR, PCS methods. The colloidal stability of the suspensions and the acid-base characteristics of the surface were evaluated in the environment of physiological solution. Substitution of La ions by Tb ions in LaF3:Tb samples does not lead to a significant distortion of the crystal structure, but it significantly affects the dimensional characteristics, specific surface area, charge and acid-base characteristics. The given data indicate the perspective of research of nanodispersed phosphors based on lanthanum fl uoride for use in optopharmacology and photodynamic therapy of tumor diseases localized in the organ s of the skull and bone tissues. In addition, research results can be useful for technical applications, in particular, in the creation of fluorescent detectors of high-energy electromagnetic radiation, development of photo- and optoelectronic devices, etc.