Towards a Shape Language for Interpreting RNA Folding

A. Mamuye, E. Merelli, L. Tesei
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引用次数: 1

Abstract

In this paper we introduce a shape language for representing RNA secondary structures in a non-standard, non-linear way. The main motivation is to propose a new interpretation of RNA folding as a self-adaptability process, within the S[B] paradigm, towards a minimum free energy configuration. An RNA secondary structure is decomposed first by distinguishing between pseudoknot free and pseudonotted sub-structures. For pseudoknot free sub-structures a proper formal language is defined. To address the representation of pseudoknotted sub-structures the crucial aspects of RNA irreducible shapes and their associated automatic groups are introduced.
一种解释RNA折叠的形状语言
在本文中,我们介绍了一种非标准的,非线性的方式表示RNA二级结构的形状语言。研究的主要动机是提出一种新的解释,将RNA折叠作为一种自适应过程,在S[B]范式中,实现最小自由能配置。首先通过区分无假结和无假结的子结构来分解RNA二级结构。对于无伪结子结构,定义了适当的形式语言。为了解决假结亚结构的表征,介绍了RNA不可约形状及其相关自动组的关键方面。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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