Cardiovascular and Biochemical Responses in Exercise Recuperation in Diabetic Rats

Blood Glucose Levels Pub Date : 2019-09-27 DOI:10.5772/INTECHOPEN.79084

Luiz Augusto da Silva, Jéssica Wouk, V. M. R. Weber

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Abstract

The objective of this study was to assess the cardiovascular and biochemical responses during aerobic exercise recuperation in diabetic rats. There were utilized 12 animals, of 60 days, divided in two groups: control and diabetic. On the test day, the animals performed a 60 minutes’ session of predominantly aerobic exercise, using an overload of 6% of their body’s weight. After and before the exercise, the animals had their systolic blood pressure (SBP) and heart rate (HR), lactate, glycerol and glucose measured. The animals were trained during 30 days by swimming tank, with an extra weight equivalent to 4% extra weight a 40-min session. A decrease in glucose value occurred in the diabetic animals after exercising, as well as an increase of lactate in the same group. 1’, 3’, 5’ and 7’ after the exercise, a significant reduction of HR in the diabetic group was noticed when compared with the control group, such behavior was also observed with double product (DP) together with SBP values 1’, 3’ and 5’ after the exercise. The diabetic animals’ recovery has been possibly affected by a reduction of blood flow and a reduction of energetic substrates contribution, as well as lactate clearance.

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糖尿病大鼠运动恢复过程中的心血管和生化反应

本研究旨在探讨糖尿病大鼠在有氧运动恢复过程中的心血管和生化反应。试验动物12只，每60 d，分为对照组和糖尿病组。在测试当天，这些动物进行了60分钟的有氧运动，负荷为体重的6%。在运动后和运动前，测量动物的收缩压(SBP)、心率(HR)、乳酸、甘油和葡萄糖。这些动物在30天的时间里接受了游泳训练，每40分钟的训练增加的体重相当于增加了4%。运动后糖尿病动物血糖值下降，乳酸升高。运动后1′、3′、5′、7′时，糖尿病组HR较对照组明显降低，运动后双积(DP)及收缩压1′、3′、5′值也有此现象。糖尿病动物的恢复可能受到血流量减少、能量底物贡献减少以及乳酸清除的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Blood Glucose Levels

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