Anita Sukarno, Mohammad Heri Kurniawan, A. Awaluddin
{"title":"EFFICACY, IMMUNOGENICITY AND SIDE EFFECT OF COVID-19 VACCINE ON PREGNANT AND LACTATING WOMEN: A SYSTEMATIC REVIEW","authors":"Anita Sukarno, Mohammad Heri Kurniawan, A. Awaluddin","doi":"10.24252/join.v6i2.25913","DOIUrl":null,"url":null,"abstract":"Purpose: To investigate the efficacy, immunogenicity, and side effect of the Covid-19 vaccine on pregnant and lactating women. Methods: We obtained 1366 articles from 7 databases such as PubMed, Google Scholar, ScienceDirect, Cochrane Library, EU Clinical Trials Register, ClinicalTrials.gov, the WHO Clinical Trial Registry. The search terms were “Covid-19 Vaccine”, “Sars-Cov-2 Vaccine”, “Vaccine Efficacy”, “Vaccine Immunogenicity”, “Vaccine Side Effect“, “Pregnant Women”, and “Lactating Women”. Study selection and study quality appraisal were guided by Joanna Briggs Institute (JBI). Results: Fifteen articles were included. Vaccinated pregnant women had a lower risk of Covid-19 infection. Immune responses were detected in maternal blood, cord blood, and breast milk. The T-cell had the potential to against viral variants. Covid-19 vaccination resulted in low disruption among lactating women. There was no difference in side effects between pregnant and nonpregnant women. Conclusions: Covid-19 vaccine lowered infection risk and robust immune responses among pregnant and lactating women.","PeriodicalId":134822,"journal":{"name":"Journal of Islamic Nursing","volume":"11 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Islamic Nursing","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24252/join.v6i2.25913","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Purpose: To investigate the efficacy, immunogenicity, and side effect of the Covid-19 vaccine on pregnant and lactating women. Methods: We obtained 1366 articles from 7 databases such as PubMed, Google Scholar, ScienceDirect, Cochrane Library, EU Clinical Trials Register, ClinicalTrials.gov, the WHO Clinical Trial Registry. The search terms were “Covid-19 Vaccine”, “Sars-Cov-2 Vaccine”, “Vaccine Efficacy”, “Vaccine Immunogenicity”, “Vaccine Side Effect“, “Pregnant Women”, and “Lactating Women”. Study selection and study quality appraisal were guided by Joanna Briggs Institute (JBI). Results: Fifteen articles were included. Vaccinated pregnant women had a lower risk of Covid-19 infection. Immune responses were detected in maternal blood, cord blood, and breast milk. The T-cell had the potential to against viral variants. Covid-19 vaccination resulted in low disruption among lactating women. There was no difference in side effects between pregnant and nonpregnant women. Conclusions: Covid-19 vaccine lowered infection risk and robust immune responses among pregnant and lactating women.