Optimum Design of the Eccentric Trapezoidal Magnetic Stimulation Coil Considering Stimulation Effect and Heat Dissipation

Xiaoliang Fang, Wei Liu, Yaoyao Luo, Chang Liu, Zhou He
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Abstract

To improve the magnetic stimulation effect, the eccentric trapezoidal magnetic coil (ETM coil) is designed based on the inspiration of special-shaped magnets. The proposed ETM coil consists of two identical coil units and each unit is in the shape of isosceles-trapezoid when projected onto the stimulated target plane. When two coil units are placed adjacent or overlapped, they are referred to as Type I-ETM coil and Type II-ETM coil, respectively. To limit the induced electromagnetic field within a smaller domain, the ETM coil is bent along the symmetrical axis at specific angles. Considering the overheating problem when repetitive stimulation is required, the ETM coil is wound with hollow copper wire and the central hollow part is used to circulate low-temperature deionized water. The finite element analysis method is adopted to obtain the 3D distributions of the induced electromagnetic field generated by ETM coil within the human brain and the internal cooling parameters design is carried out with coupled multi-physical field analysis. Results show that the ETM coil can produce the same stimulation intensity as the traditional FOE coil with less driving current, and it can also significantly improve the intracranial stimulation focalization and reduce the risk of side effects. Meanwhile, because of the internal cooling design, the temperature of the ETM coil could be maintained at room temperature after 3000 effective pulses were applied, while the temperature of the FOE coil exceeds the safe range. To verified our method, an anatomically realistic human head model with different electrical properties assigned to each tissue of the brain is employed in this paper. We also checked the maximum induced charge density on the targeted plane generated by the optimized coil to make sure that it will not cause any induced neurologic damage.
考虑激励效应和散热的偏心梯形磁激励线圈优化设计
为提高磁刺激效果,根据异型磁铁的启发,设计了偏心梯形磁线圈(ETM线圈)。提出的ETM线圈由两个相同的线圈单元组成,每个单元在投影到受激目标平面时呈等腰梯形。当两个线圈单元相邻或重叠放置时,它们分别被称为i型etm线圈和ii型etm线圈。为了将感应电磁场限制在较小的范围内,ETM线圈沿对称轴以特定角度弯曲。考虑到需要重复刺激时的过热问题,ETM线圈用空心铜线缠绕,中心空心部分用于低温去离子水循环。采用有限元分析方法获得了ETM线圈在人脑内产生的感应电磁场的三维分布,并结合多物理场耦合分析进行了内部冷却参数设计。结果表明,ETM线圈可以产生与传统FOE线圈相同的刺激强度,且驱动电流更小,还可以显著提高颅内刺激聚焦,降低副作用风险。同时,由于内部冷却设计,在施加3000个有效脉冲后,ETM线圈的温度可以保持在室温,而FOE线圈的温度超出了安全范围。为了验证我们的方法,本文采用了一个解剖学上真实的人类头部模型,该模型具有分配给大脑每个组织的不同电特性。我们还检查了优化线圈在目标平面上产生的最大感应电荷密度,以确保它不会引起任何诱导神经损伤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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