Optimization of the Alpha-Amylase Production from Microbial Source: A Systematic Review of Experimental Studies

Trends in Medical Sciences Pub Date : 2022-08-17 DOI:10.5812/tms-129317

Razie Hormoznejad, Shiri Saberi, A. Moridnia, Maryam Azish, Babak Elyasi Far

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引用次数: 2

Abstract

Context: The growth and production of enzymes by microorganisms depend highly on the compounds and factors entering the system. Objectives: The present systematic review aimed to assess the optimized medium content to enhance alpha-amylase production from the microorganisms. Methods: The PubMed, Embase Web of Science, Scopus, and Google Scholar databases were searched from inception to April 2022, restricted to the English language. The reference list of the included studies was cross-checked, and a partial gray literature search was undertaken. Alpha-amylase production from the microorganisms and optimized medium content by statistical design were the key evaluated outcomes. Results: Among 995 initially gathered litterateurs, 12 studies were included in this review, which involved bacteria (seven studies), yeasts (two studies), fungi (two studies), and protists (one study). The results indicated that the optimized medium composition by statistical design might increase alpha-amylase production. Conclusions: Growth conditions, including pH, temperature, and starch concentration, are essential to be optimized to improve alpha-amylase yield.

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微生物源α -淀粉酶生产的优化:实验研究的系统综述

背景:微生物的生长和酶的产生高度依赖于进入系统的化合物和因子。目的:本系统综述旨在评价提高微生物α -淀粉酶产量的培养基优化含量。方法:检索PubMed、Embase Web of Science、Scopus和Google Scholar数据库，检索时间从成立到2022年4月，仅限于英文。对纳入研究的参考文献表进行交叉核对，并进行部分灰色文献检索。微生物的α -淀粉酶产量和通过统计设计优化的培养基含量是评估的关键结果。结果:在最初收集的995篇文献中，本综述纳入了12篇研究，其中涉及细菌(7篇)、酵母(2篇)、真菌(2篇)和原生生物(1篇)。结果表明，经统计设计优化的培养基组成可提高α -淀粉酶的产量。结论:优化生长条件，包括pH、温度和淀粉浓度，是提高α -淀粉酶产率的关键。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Trends in Medical Sciences

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