An Approach of Ion Selective Electrode for Human Body, Cells and Biomedical Researches

P. K. Nagar, Ranjan Maheshwari, V. Pandey
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引用次数: 2

Abstract

Basically this study shows the use of Ion Selective Electrodes for the study of cells, blood and other human body parts and also in other biomedical researches. Because we know that body cell content different type of nutrient elements such as Amino acid, phosphorous etc., blood contains iron, haemoglobin, sodium etc. So the elements in the cells, blood and other parts of human body can be determine individually by using the ion selective electrode because ion selective electrode respond to a particular ion or element. In ion selective electrode method Nernst Equation is generally used. This method works as a new technology for sensing the selective element in suitable manner within a specified limit. In biomedical researches ion selective electrode can be used for DNA, RNA study purpose because DNA and RNA are the nuclear acids and these acids can be analysed by using ion selective electrode method. Ion selective electrode method works on the potentiometric behaviour and linear regression model. Linear regression model is made by using the Nernst equation with the help of least square method. In this method there are many potentiometric calculations are performed and finally their mean is used as result for the concentration of elemental analysis. Generally ion selective electrode has wide range of operation for 5×10-5 mol/l. to 1×10-1 mol/l.
离子选择电极在人体、细胞和生物医学研究中的应用
基本上,这项研究展示了离子选择电极在细胞、血液和其他人体部位的研究以及其他生物医学研究中的应用。因为我们知道,人体细胞中含有不同类型的营养元素,如氨基酸、磷等,血液中含有铁、血红蛋白、钠等。因此,细胞,血液和人体其他部分中的元素可以通过离子选择电极单独确定,因为离子选择电极对特定的离子或元素做出反应。在离子选择电极法中,通常使用能斯特方程。该方法是在规定的范围内以合适的方式对选择元素进行传感的一种新技术。在生物医学研究中,离子选择电极可用于DNA和RNA的研究目的,因为DNA和RNA是核酸,这些酸可以用离子选择电极方法进行分析。离子选择电极法研究的是电化学行为和线性回归模型。利用能斯特方程,借助于最小二乘法建立线性回归模型。在此方法中,需要进行多次电位计算,最后用它们的平均值作为元素分析浓度的结果。一般离子选择电极的操作范围较广,为5×10-5 mol/l。到1×10-1 mol/l。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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