Benefits of Probiotic Containing Foods for the Prevention of Enteric Cancer: A Review

Abstract

Probiotics that could act as cancer preventive agents, one of the representation of new novel therapeutic options and the beneficial in the prevention and alleviation of symptoms of colon cancer has been proven. The development, progression and treatment of colorectal cancer could be possible by using probiotics that have the potential significantly on it. Moreover, there are different strains of probiotics bacteria which possess varying responses towards the prevention of colorectal cancer. The consumption of prebiotics (special form of dietary fiber that induces the growth of favourable bacteria) and probiotics is the main attention has been focused on to decrease cancer risk through diet variations. The cultured milk, yogurt and other fermented dairy products and foods which contain probiotics have been proven by some recent reports that demonstrated there is an inverse association between cancer risk and them. In addition, the probiotic bacteria in association with prebiotic effectively enhances the humoral immune response has also been shown when that be on an oral administration. The anticancer activity of probiotics obtains by various mechanisms such as augmentation of natural killer cell activity, modulation of host immune response through macrophages (induction of ILs) and restraint of the composition of indigenous microbiota and their metabolic activity are important. Moreover, the enhanced activity of NK cells was also observed in symbiotic association of probiotics with prebiotics (indigestible dietary fiber/carbohydrate). Usage of probiotic nutritional intervention pre and post treatment may provide protection for healthy cells and tissues.