PROBIOTICS AND ORAL HEALTH: A REVIEW

A. Jamkhande, Saurabh P. Kakade, Aishwarya Gundawar
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Abstract

Probiotics are non-pathogenic living microbes used to treat several medical conditions. They have been added in a few food products due to their favourable results on human health. The mechanism of action of probiotics is associated with their capacity to cope with pathogenic microorganisms for adhesion sites, to antagonize these pathogens or to regulate the host’s immune response. Probiotics might be helpful in intercepting and treating oral infections, including dental caries, periodontal disease and halitosis. Probiotics contribute to a healthy microbial balance by interacting with oral micro biome which impacts the general health, being a significant contributor to oral health. The development of drug resistance and the side effects of available antimicrobials have confined their use in an array of prophylactic options. Currently, no such evidence exists to support the use of probiotics to prevent, treat or manage oral cavity diseases. Probiotics don’t have any adverse effects and there is no evidence of being used for the treatment or as a preventive measure for the oral health. In this review, author tried to explore the use of probiotics in prevention, treatment and management of oral cavity diseases and the possibilities of developing designer probiotics for the next generation of oral healthcare.
益生菌与口腔健康:综述
益生菌是用于治疗多种疾病的非致病性活微生物。由于对人体健康有益,它们已被添加到一些食品中。益生菌的作用机制与它们对付病原微生物的粘附位点、拮抗这些病原体或调节宿主免疫反应的能力有关。益生菌可能有助于拦截和治疗口腔感染,包括龋齿,牙周病和口臭。益生菌通过与影响整体健康的口腔微生物群相互作用来维持健康的微生物平衡,是口腔健康的重要贡献者。耐药性的发展和现有抗菌素的副作用限制了它们在一系列预防选择中的使用。目前,没有这样的证据支持使用益生菌来预防、治疗或管理口腔疾病。益生菌没有任何副作用,也没有证据表明它被用于治疗或预防口腔健康。本文就益生菌在口腔疾病的预防、治疗和管理中的应用,以及为下一代口腔保健开发设计益生菌的可能性进行综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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