SARS-COV-2 Positive Patient with Fournier’s Gangrene and Multiorgan Complications

Eggleton J
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Abstract

Fournier gangrene is a rare type of necrotizing fasciitis of the genital or anorectal region that rapidly progresses towards diffuse tissue necrosis and mortality if untreated. As seen in this case, the disease is difficult to diagnose in its early stages due to a lack of pathognomonic signs that differentiate it from a localized scrotal abscess, cellulitis, pyoderma gangrenosum, and orchitis. These initial findings of Fournier’s gangrene make rapid diagnosis difficult, thus we recommend a low threshold for further workup based on exam findings and clinical suspicion. Emergent imaging modalities and cultures can aid in the diagnosis but should not delay surgical debridement and broad-spectrum antibiotics -the gold standard of treatment for Fournier’s gangrene. This case also presents possible correlations between SARS-CoV-2 and Fournier’s gangrene, but further research must be conducted to delineate clinical course management in patients with SARS-CoV-2 and Fournier’s gangrene.
SARS-COV-2阳性富尼耶坏疽患者及多器官并发症
富尼耶坏疽是一种罕见的生殖器或肛门直肠区域坏死性筋膜炎,如果不治疗,会迅速发展为弥漫性组织坏死和死亡。正如本例所见,由于缺乏与局限性阴囊脓肿、蜂窝组织炎、坏疽性脓皮病和睾丸炎区分的病理征象,该病在早期阶段难以诊断。Fournier坏疽的这些初步发现使快速诊断变得困难,因此我们建议根据检查结果和临床怀疑进行低阈值的进一步检查。紧急成像模式和培养可以帮助诊断,但不应延迟手术清创和广谱抗生素-治疗富尼耶坏疽的黄金标准。该病例也表明SARS-CoV-2与富尼耶坏疽之间可能存在相关性,但必须进行进一步的研究以确定SARS-CoV-2和富尼耶坏疽患者的临床病程管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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