Extensive bilateral anterior and posterior circulation ischemic stroke caused by severe vasospasm (Delayed cerebral ischemia) due to aneurysmal subarachnoid haemorrhage (aSAH) - A case report

S. Balaji, S. Venkatesan
{"title":"Extensive bilateral anterior and posterior circulation ischemic stroke caused by severe vasospasm (Delayed cerebral ischemia) due to aneurysmal subarachnoid haemorrhage (aSAH) - A case report","authors":"S. Balaji, S. Venkatesan","doi":"10.18231/j.ijn.2023.019","DOIUrl":null,"url":null,"abstract":"Aneurysmal subarachnoid haemorrhage (aSAH) is a disease with high morbidity and mortality even in this modern era. Since treating vasospasm is a challenging task, we emphasize in developing newer aganets for the treatment of vasospasm. In the hyper acute phase, patients with SAH can have catecholamine surge-related arrhythmia, neurogenic pulmonary edema, and irreversible damage to the hypothalamus and brainstem. Delayed cerebral ischemia (DCI) is a serious complication of aneurysmal subarachnoid haemorrhage (aSAH). Though there are many clinical trials to look upon the therapies for DCI and vasospasm in aSAH, none have led to an improvement in outcome of the patient.The prognosis of patients with SAH is grave even with the recent advancements in medical treatments. One of the main cause for this situation, that there are no usable neuroprotective drugs that can be used as soon as SAH is diagnosed. We report a case of ruptured Post Communicating Artery (PCOM) aneurysm with diffuse SAH causing severe vasospasm leading to extensive bilateral anterior and posterior ischemic stroke causing severe morbidity. Since there is no therapeutic breakthrough in treatment of aneurysmal SAH, we emphasize in developing a same.","PeriodicalId":415114,"journal":{"name":"IP Indian Journal of Neurosciences","volume":"28 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IP Indian Journal of Neurosciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/j.ijn.2023.019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Aneurysmal subarachnoid haemorrhage (aSAH) is a disease with high morbidity and mortality even in this modern era. Since treating vasospasm is a challenging task, we emphasize in developing newer aganets for the treatment of vasospasm. In the hyper acute phase, patients with SAH can have catecholamine surge-related arrhythmia, neurogenic pulmonary edema, and irreversible damage to the hypothalamus and brainstem. Delayed cerebral ischemia (DCI) is a serious complication of aneurysmal subarachnoid haemorrhage (aSAH). Though there are many clinical trials to look upon the therapies for DCI and vasospasm in aSAH, none have led to an improvement in outcome of the patient.The prognosis of patients with SAH is grave even with the recent advancements in medical treatments. One of the main cause for this situation, that there are no usable neuroprotective drugs that can be used as soon as SAH is diagnosed. We report a case of ruptured Post Communicating Artery (PCOM) aneurysm with diffuse SAH causing severe vasospasm leading to extensive bilateral anterior and posterior ischemic stroke causing severe morbidity. Since there is no therapeutic breakthrough in treatment of aneurysmal SAH, we emphasize in developing a same.
动脉瘤性蛛网膜下腔出血(aSAH)引起严重血管痉挛(延迟性脑缺血)引起的广泛双侧前后循环缺血性卒中1例报告
动脉瘤性蛛网膜下腔出血(aSAH)是一种高发病率和死亡率的疾病,即使在当今时代。由于治疗血管痉挛是一项具有挑战性的任务,我们强调开发治疗血管痉挛的新药物。在超急性期,SAH患者可出现儿茶酚胺手术相关的心律失常、神经源性肺水肿以及下丘脑和脑干的不可逆损伤。延迟性脑缺血(DCI)是动脉瘤性蛛网膜下腔出血(aSAH)的严重并发症。虽然有许多临床试验来研究aSAH中DCI和血管痉挛的治疗方法,但没有一项能改善患者的预后。即使在最近的医学治疗进展下,SAH患者的预后仍然很严重。造成这种情况的主要原因之一是,一旦诊断出SAH,就没有可用的神经保护药物可以使用。我们报告一例交通后动脉(PCOM)动脉瘤破裂并弥漫性SAH引起严重的血管痉挛,导致广泛的双侧前后缺血性卒中,并导致严重的发病率。由于在动脉瘤性SAH的治疗上没有治疗上的突破,我们强调发展一种相同的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信