Musculoskeletal Complications And General Health Status Of Individuals With Sickle Cell Disease

O. Ayanniyi, A. Ayeni, M. O. Oni-Orisan
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Abstract

Sickle cell disease is a chronic disease that is associated with high degree of morbidity and mortality. The objective of this study was to find the relationship between musculoskeletal complications and general health status of patients with sickle cell disorders. The HSQ 2.0 questionnaire, (a general health survey questionnaire), was used to assess the subjects’ health status while a separate questionnaire was used to compile data on complications. Descriptive and inferential statistic of Spearman’s correlation was used to find relationship between complications and health status. Level of significance was set at 0.05 alpha. Seventy-two subjects with sickle cell disorder participated in the study. Fifty-six (77.8%) were of genotype Hb SS. Most of the subjects, 51 (70.8%) normally experienced back pain, 22 (30.5%) had chest pain while only 2.8% had visual problem. Generally, subjects scored low on all health status sub-scales except the mental health sub-scale where the mean score was near 60% (59.84 ± 17.41%). The lowest mean score (47.99 ± 24.03%) was obtained on role limitation due to physical health sub-scale. There were significant correlations between complications and health status. It was concluded that the health of individuals with sickle cell disease is compromised on all the eight domains of health status and that painful complications affect their social and physical functioning and impose limitation on them. It was also concluded that the more the number of body parts with pain the lower the health status become. KEYWORDS: Musculoskeletal complications; Health status; Sickle cell disease.
镰状细胞病患者的肌肉骨骼并发症和一般健康状况
镰状细胞病是一种高发病率和高死亡率的慢性疾病。本研究的目的是发现肌肉骨骼并发症与镰状细胞病患者的一般健康状况之间的关系。采用HSQ 2.0问卷(一般健康调查问卷)评估受试者的健康状况,并使用单独的问卷收集并发症的数据。采用Spearman相关的描述性和推断性统计分析并发症与健康状况的关系。显著性水平设为0.05 alpha。72名镰状细胞病患者参与了这项研究。56例(77.8%)为Hb SS基因型,51例(70.8%)为正常背痛,22例(30.5%)为胸痛,仅2.8%为视力问题。总体而言,除心理健康外,其他健康状况量表得分均较低,平均得分接近60%(59.84±17.41%)。身体健康角色限制得分最低(47.99±24.03%)。并发症与健康状况有显著相关性。结论是,镰状细胞病患者的健康在健康状况的所有八个方面都受到损害,痛苦的并发症影响他们的社会和身体功能,并对他们施加限制。研究还得出结论,疼痛部位越多,健康状况越差。关键词:肌肉骨骼并发症;健康状况;镰状细胞病。
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