Acoustic Microscopy: Recollections

C. Quate
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引用次数: 21

Abstract

W HEN I was first asked to write for this special issue, I was occupied with the reorientation of our entire research program and another article on acoustics seemed like a diversion. I resisted. But the editors were very persuasive, and the special issue has proved to be irresistible. The articles of this issue form a set that is complete, but but there are a few points that can be added to fill in some of the background. This is an opportunity to talk with a special audience, to acknowledge the contributions from those who have worked with us along the way, and to express our appreciation for the people who have provided the funds. Those people in Washington and in the foundations who work so hard to fund research programs make it all possible. There is little that could have been accomplished without them. In London during the month of July 1984, manufacturers exhibited their prototypes of the commercial instruments. 1984 was a milestone year for acoustic microscopy, for the information gathered with these new models outweighs anything that has appeared before. Each of the prototypes will incorporate the essential concept that we have been exploiting for several years; the concept of a single spherical lens concentrating the energy from a large source to a narrow waist with a size determined by the acoustic wavelength. This type of lens does not suffer from spherical aberrations; it is diffraction limited . The original motivation for our work came from the biologists. We were told that it was a matter of some importaye to improve the resolution beyond the limit of 3000 A set by the optical instrument with a water immersion lens. They suggested a factor of two for the improvement. It will be some time before we know whether that is true. In the meantime, the instruments will be used in fields other than biology. I suspect that polymer chemists will be the first to acquire the commercial acoustic instruments, just as they were first to acquire the scanning electron microscopes (SEM). Why did it take so long to reach this stage? That is the interesting question. Certainly the technology was available. Sokolov’s suggestion goes back 35 years. I think that part of it may have been our own inhibitions or misconceptions. One misconception is that the image must be presented in real time, 30 frames per second, as defined by the tel-
声学显微镜:回忆
当我第一次受邀为本期特刊撰稿时,我正忙于重新确定我们整个研究计划的方向,而另一篇关于声学的文章似乎是一种消遣。我反对。但是编辑们很有说服力,这期特刊已经被证明是不可抗拒的。这期的文章构成了一个完整的集合,但是还有几点可以补充来填补一些背景。这是一个与特别听众交谈的机会,感谢一路以来与我们一起工作的人们的贡献,并向提供资金的人们表示感谢。那些在华盛顿和基金会工作的人们努力为研究项目提供资金,使这一切成为可能。没有他们,我们几乎不可能取得任何成就。1984年7月,制造商在伦敦展出了他们的商用仪器原型。1984年对于声学显微镜来说是具有里程碑意义的一年,因为这些新模型收集的信息超过了之前出现的任何信息。每个原型都将包含我们已经开发了好几年的基本概念;一个单一的球形透镜的概念,将能量从一个大的来源集中到一个由声波波长决定大小的窄腰。这种类型的镜头没有球像差;它是衍射极限。我们工作的最初动机来自生物学家。我们被告知,在光学仪器设定的3000 a的分辨率限制之外,用一个水浸透镜来提高分辨率是一件很重要的事情。他们建议提高两倍。我们要过一段时间才能知道那是不是真的。与此同时,这些仪器将用于生物学以外的领域。我猜想聚合物化学家将是第一个获得商用声学仪器的人,就像他们第一个获得扫描电子显微镜一样。为什么花了这么长时间才达到这个阶段?这是个有趣的问题。当然,技术是可用的。Sokolov的建议可以追溯到35年前。我认为部分原因可能是我们自己的抑制或误解。一个误解是图像必须实时呈现,每秒30帧,这是由电话定义的
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