[Glutamic acid oxidation and its regulation in purified mitochondria and nerve endings of rat cerebral cortex].

Abstract

A comparative study of respiration of mitochondrial and synaptosomal fractions of adult rat brain cerebral cortex has shown that glutamic acid is oxidized in both fractions and that its oxidation is potentiated by ADP. Addition of ADP has, however, a different effect on the endogenous respiration of these two fractions; while it has no effect on the endogenous respiration of the synaptosomal fraction, it increases considerably the weak endogenous respiration of the mitochondrial fraction.