Electrophoretic variants of alkaline phosphatase in normal human populations.

Abstract

Polyacrylamide gel electrophoresis of sera obtained from normal individuals shows an incidence (33%) of double and triple bands of alkaline phosphatase in the beta-lipoprotein zone in addition to the usual ones near beta-globulin. The correlation between the occurrence of a slow moving band in addition to the normal one, of different intensities, p+ and p++ with O and B groups has been further confirmed. No relationship was observed between the width or the number of bands with the total amount of alkaline prosphatase as determined biochemically.