The Investigation of Physical Mechanism of Transcapillary Exchange by Phase-Sensitive Laser Method

Abstract

The processes of diffusion and filtration are slow, and therefore a full cycle of gas exchange and metabolism at the level of capillaries of the blood circulation system cannot be realized in such a short time. A special laser setup was created for noncontact, noninvasive investigation of microcirculation and transcapillary exchange in a living object. With the help of investigations by using this setup, a phenomenon unknown before, that of the formation of an acoustic field in the lumens of microvessels (arterioles, capillaries, and venules) was discovered. With the help of the laser method, we detected that the transverse motion of the walls of microvessels in the high-frequency range really takes place. The authors advanced the problem of active interaction of moving erythrocytes in microvessels with smooth muscle cells of their walls for the first time. In blood vessels, smooth muscle elements are packed spirally. We suggest that there exists a special mechanism of regulation of metabolic processes.