Evaluation of the efficacy of Latakaranja as Antispasmodic Drug in Kastaartava - A Randomised Clinical Control Trial

Dhiraj Ojha, P. Rawal, Shrishail. S. Pujeri, Sunita Shirguppi
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Abstract

Kastaartava (Dysmenorrohea) is a greek word, describes about painful menstruation which the Pratyatmaka Lakhshans of various Yonivyapad that are Vatala Yonivyapad, Udavartini Yonivyapad, Paripluta Yonivyapad, Mahayoni and Vataja Artava Dusti that affects 75% of adolscents, 25-50% of adult women and 5-20% having dysmenorrhea. It is a common reason for losing time at school or work or visiting family doctor. Morbid Vatadosha especially Apanavata is a causative factor of Kastaartava. Vatahara properties are beneficial considering the morbidity and complications that are caused by Kastaaratava, mentioned above herbal preparation has been tried here. This research work is randomized control clinical study with Pre-test and Post-test design. 40 patients suffering from Kastaaratava (Dysmenorrohoea) were selected randomly for study. The selected patients were divided into 2 groups, 20 patients each. The selected 20 patients in Group A (Trial group) were administered Latakaranja Beeja Churna orally. The selected 20 patients in Group B (Controlled group) were administered Rajapravartini Vati. The duration of treatment was for 03 days of menstruation for 2 menstrual cycles and followup for the next menstrual cycle. After the completion of the clinical trial, it was found that in Rajapravartini Vati, there was highly significant result in Cramping pain in abdomen, Irritability, Tenderness in Breast, Back pain and Headache, where as Latakaranja Beeja Choorna there is also significant result in Cramping pain in Abdomen, Irritability, Tenderness in Breast, Back Pain, Headache and Vomiting but statistically considering average mean Latakaranja Choorna shows comparatively lesser effective than Rajapravartini Vati. By the statistical results it can be concluded that Rajapravartini Vati has better result when compared to Latakaranja Choorna in the present study.
评价Latakaranja作为抗痉挛药物在kastartava中的疗效-一项随机临床对照试验
Kastaartava(痛经)是一个希腊词,描述了各种Yonivyapad的Pratyatmaka Lakhshans,包括Vatala Yonivyapad, Udavartini Yonivyapad, Paripluta Yonivyapad, Mahayoni和Vataja Artava Dusti,影响了75%的青少年,25-50%的成年女性和5-20%的痛经患者。这是一个常见的原因,浪费时间在学校或工作或去看家庭医生。病态的Vatadosha,尤其是Apanavata,是Kastaartava的一个致病因素。考虑到Kastaaratava引起的发病率和并发症,vastaaratava的特性是有益的,上面提到的草药制剂已经在这里进行了尝试。本研究采用前测和后测设计的随机对照临床研究。随机选取40例痛经患者进行研究。选取的患者分为2组,每组20例。A组(试验组)选取20例患者口服白参。B组(对照组)20例患者给予拉贾伐替尼。治疗时间为3天,连续2个月经周期,下个月经周期随访。临床试验完成后,发现Rajapravartini Vati在腹部绞痛、易怒、乳房压痛、背部疼痛和头痛方面的效果非常显著,而Latakaranja Beeja Choorna在腹部绞痛、易怒、乳房压痛、背部疼痛方面的效果也非常显著。头痛和呕吐,但统计上考虑到平均水平,拉塔卡兰加·乔那的效果相对不如拉贾瓦蒂尼·瓦蒂。通过统计结果可以得出Rajapravartini Vati与本研究中的Latakaranja Choorna相比具有更好的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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