The Different Clinical Expressions of the Aspergillus/Host Interactions in Humans

Abstract

Aspergillus is very ubiquitous. It is a highly aerobic fungus and found as mold on surfaces. It spreads most commonly through spores in the air that are not detected with the naked eye. These spores get into the respiratory tract where they colonize and often cause different kinds of reactions. Human beings respond to these inhalations in several ways depending upon the status of one’s immune system. In fact some of these responses are diametrically opposed from each other to the point that we decided to report our experience of the different expressions of the Aspergillus/human interaction in a spectral fashion. We have represented these findings in a parabola pictured below where to the right of the parabola from 0 to 90, we included the interactions of Aspergillus with an immune deficient host, and to the left of the parabola from 90 to 180, we considered the interactions of Aspergillus with a host of a hyperergic immune system.