Development of a spectrofluorometer with USB interface for in vivo measurements in surgical procedures

2010 2nd Circuits and Systems for Medical and Environmental Applications Workshop (CASME) Pub Date : 2010-12-01 DOI:10.1109/CASME.2010.5706669

D. Fabila, J. M. de la Rosa, S. Stolik, E. Moreno, T. Lopez, M. Álvarez, A. Arellano, G. De La Rosa, R. Mercado, J. Soto

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引用次数: 2

Abstract

In this paper we present the development of a portable spectrofluorometer with USB interface for in vivo measurements in biological tissue. The equipment consists of a mini-spectrometer HR4000CG-UV-NIR, with a working range from 200 to 1100 nm with a resolution of 0.5 nm FWHM. As the excitation source a light emitting diode at 365 nm, with maximum radiant power of 200 mW was used. A bifurcated fiber optic (R200-UV/VIS) with six 200 µm diameter irradiation fibers and one 200 µm collection fiber is used. The system is powered and controlled with a laptop, avoiding the use of an external power supply. A program to select the light source, to process and measure spectra in real time was developed using the graphic language G of LabVIEW 8.2. Also, in this issue are presented in vivo measurements of diffuse reflection and fluorescence of non-neoplastic and neoplastic cerebral tissue of patients affected with glioblastoma multiform tumors (GBM).

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用于外科手术中体内测量的带有USB接口的荧光分光计的研制

本文介绍了一种便携式USB接口荧光光谱仪的研制，用于生物组织的体内测量。该设备由一台HR4000CG-UV-NIR微型光谱仪组成，工作范围为200 ~ 1100nm，分辨率为0.5 nm FWHM。采用波长为365 nm，最大辐射功率为200 mW的发光二极管作为激发源。采用分岔光纤(R200-UV/VIS)， 6根直径200µm的辐照光纤和1根直径200µm的采集光纤。该系统由笔记本电脑供电和控制，避免使用外部电源。利用LabVIEW 8.2的图形语言G开发了一个实时选择光源、处理和测量光谱的程序。此外，本文还介绍了多形性胶质母细胞瘤(GBM)患者非肿瘤性和肿瘤性脑组织的漫反射和荧光的体内测量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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2010 2nd Circuits and Systems for Medical and Environmental Applications Workshop (CASME)

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