Impact of malnutrition and its correction on mortality in older adults

A. Turusheva
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Abstract

BACKGROUND: Malnutrition is associated with decreased levels of physical function, cognitive decline, and an increased risk of all-cause mortality, making it important to identify risk factors for malnutrition, especially in old age. AIM: To identify factors associated with an increase and decrease in the risk of developing malnutrition, as well as to assess the impact of malnutrition and its correction on mortality in older adults. MATERIALS AND METHODS: A prospective cohort study of a random sample of 611 people aged 65 years and older. Mini Nutritional Assessment, Geriatric Depression Scale, Mini-Mental State Examination, dynamometry, Barthel Index, chronic noncommunicable diseases, clinical blood count, C-reactive protein. 2 examinations, 9 years of total follow-up. RESULTS: Risk factors for deterioration in nutritional status are decrease in emotional status (odds ratio 5.439; 95% confidence interval 2.79410.588), progression of autonomy decline (odds ratio 2.428; 95% confidence interval 1.3424.393), low physical function (odds ratio 2.877; 95% confidence interval 1.5775.250). A high level of physical function reduces the risk of malnutrition by 64.1%. Malnutrition increases the risk of five-year mortality by 2.7 times. A normal nutritional status reduces the risk of nine-year mortality by 50.2%. Improve nutrition status leads to a lower risk of mortality. CONCLUSIONS: The main factors in the deterioration of nutritional status are a decrease in emotional status, loss of autonomy and a low level of physical function. Early detection of older adults with malnutrition and its correction can reduce the risk of mortality.
营养不良对老年人死亡率的影响及其纠正
背景:营养不良与身体功能水平下降、认知能力下降和全因死亡风险增加有关,因此确定营养不良的危险因素非常重要,尤其是在老年人中。目的:确定与营养不良风险增加和减少相关的因素,并评估营养不良及其纠正对老年人死亡率的影响。材料和方法:一项前瞻性队列研究,随机抽样611名65岁及以上的人。迷你营养评估、老年抑郁量表、迷你精神状态检查、动力测量、Barthel指数、慢性非传染性疾病、临床血球计数、c反应蛋白。2次检查,总随访9年。结果:营养状况恶化的危险因素为情绪状态下降(优势比5.439;95%可信区间2.79410.588)、自主性下降的进展(优势比2.428;95%可信区间1.3424.393),身体机能低下(优势比2.877;95%置信区间为1.5775.250)。高水平的身体机能可将营养不良的风险降低64.1%。营养不良使5年死亡率增加2.7倍。正常的营养状况可使9年死亡率降低50.2%。改善营养状况可降低死亡风险。结论:营养状况恶化的主要因素是情绪状态下降、自主性丧失和身体机能水平低下。早期发现老年人营养不良并加以纠正,可降低死亡风险。
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