An Unusual Association of Lung and Ovarian Malignancy in a Young Nonsmoker Female

Abstract

Lung cancer in a 25-year-old nonsmoker female is extremely rare. Ovarian malignancy in this age group is also infrequent and if occurs, is usually of germ cell type. If a patient presents with both lung and ovarian mass, the initial impression is the metastasis from one organ to the other. Chest X-ray, ultrasonogram, whole abdomen, CT scan of thorax and abdomen, bronchoscopic biopsy of lung mass and excision biopsy of ovarian mass are all needed to accurately diagnose condition. Therapy is also challenging for such patients. After accurate diagnosis for both the organs, surgery, chemotherapy, or radiotherapy should be considered after individualization of the case. Squamous cell carcinoma lung in advanced stage associated with early stage ovarian serous cystadenocarcinoma has not been described in literature. The rarity of the case, absence of cigarette smoking or radiation exposure, negative family history, unusual association and fatality of the cases prompted us to report this case.