1d Virus transmission by virus-inactivated plasma products

Abstract

The viral safety of virus-inactivated plasma products has been markedly enhanced by the improvement in tests for screening donations and by the improvement in techniques for manufacture of plasma derivatives including methods for virus inactivation. Nevertheless, there remains a weakness in removing inactivating heat-resistant non-enveloped viruses, such as parvovirus B19. Manufacturers' efforts should continue to be concentrated on this challenge.