[Meningo-cerebral adhesions and the possibility of prevention during plastic replacement of meningeal defects (experimental study)].

Abstract

A study of the causes and conditions of formation of meningeal adhesions, as well as of the possibilities of their prevention by replacement of the meningeal defects with cold-preserved homografts of fresh auto- and homografts, and synthetic film "Fluoroplast-4", as practised in 50 experiments in 46 dogs, has demonstrated that the adhesive process depends on the presence and intensity of brain and meningeal injuries. The possibility of preventing the formation of adhesions was shown to be independent of the type of the plastic material used. The adhesive processes are equally manifest in all methods of plastic repair. Neither do they depend on the method of connecting the transplant with the edges of the meningeal defect. The employment of the "Cyacrine" tissue adhesive causes grosser adhesions. Alloplastic repair is inferior to homoplastic with suturing the margin of the meningeal defect to the transplant, since it does not permit a tight closure of the subdural space.