Hip Muscle Atrophy and Hip Osteoarthritis-Evidence and Continuing Challenges

R. Marks
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Abstract

Background: Hip osteoarthritis, a highly disabling disease with no distinct cause, and a disease associated with high degrees of pain, stiffness, and disability continues to affect the lives of many adults of all ages highly adversely and may be influenced adversely by some forms of muscle dysfunction, such as hip muscle atrophy. Aim: To examine the prevailing research support for a mediating or causative role of muscle atrophy in hip osteoarthritis. Methods: An in-depth literature review focusing on hip osteoarthritis muscle atrophy associations was conducted. Results: A fair number of past and recent research reports indicate efforts to examine and intervene to minimize one or more attributes of hip muscle atrophy appears promising in the context of efforts to foster improved outcomes of hip joint osteoarthritis, regardless of the application of high-tech surgery. Conclusion: Future research efforts are strongly indicated.
髋关节肌肉萎缩和髋关节骨关节炎——证据和持续的挑战
背景:髋关节骨关节炎是一种没有明确病因的高度致残性疾病,与高度疼痛、僵硬和残疾相关的疾病,持续对所有年龄段的许多成年人的生活产生高度不利影响,并可能受到某些形式的肌肉功能障碍(如髋关节肌肉萎缩)的不利影响。目的:探讨髋关节骨性关节炎中肌肉萎缩的中介或致病作用的主流研究支持。方法:对髋关节骨性关节炎与肌肉萎缩的关系进行深入的文献回顾。结果:相当数量的过去和最近的研究报告表明,在努力促进髋关节骨关节炎改善结果的背景下,无论高科技手术的应用如何,检查和干预以最小化髋关节肌肉萎缩的一个或多个属性似乎很有希望。结论:指出了未来的研究工作。
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