Study on Prevalence and Antimicrobial Sensitivity Pattern of Bacteria Causing Urinary Tract Infection in a Tertiary Care Hospital in Sylhet.

Abstract

Background: UTI is one of the common bacterial infections occurring hospitals and the community of Bangladesh. Aims and objectives: The aim of this study is to determine the prevalence of UTIs in male and female patients as well as the effect of gender and age on its prevalence. And evaluate sensitivity to common antibiotics. Materials & methods: A cross-sectional observational study was conducted in the Department of Microbiology, Sylhet Women’s Medical College Hospital for a period from May 2021 to October 2021. Urine samples were collected from all suspected UTI patients attending to OPD/ IPD of various departments of Sylhet women’s Medical College Hospital. Isolation and antimicrobial susceptibility were performed using standard microbiological methods. Results: During the study period, a total number of samples sent to the microbiology laboratory from out and in patients of the various departments were 3139 of which 697 (18.0%) of the sample were tested positive and 2442 (82.0%) of the samples were negative. The overall prevalence of UTI for both male and female patients was found to be 18%. In this study, a high prevalence of UTIs showed in females (75%) than in males (25%).The highest susceptible age group of patients to UTI was the age group more than 60 years for both sex (30.3%). Escherichia coli was found the dominant bacteria among the isolated causative pathogens with a rate of (46.1%), the second highest is Klebsiella spp. (31.7%) followed by Staphylococcus saprophyticus 6.3%, Enterococcus faecalis 5.75%, Pseudomonas species 5.5% and Staphylococcus aureus 4.7%. Among them, a good number of isolated pathogens were multidrug resistance. Conclusion: This study reveals a significant prevalence of bacterial isolates in urine with multi drug resistance. Routine bacterial surveillance of causative agents and antibiotic susceptibility to prevent further emergence and spread of resistant bacterial pathogens.