Bioactive Peptides; Physiological Benefits and Commercial Applications

M. F. J. Chughtai
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Abstract

Milk and milk related products are strongly considered as rich source of bioactive peptides which have potential to be used as ingredients in nutraceutical foods. Dairy peptides play a key role to increase the antioxidant efficiency in multiplication order. These health promoting components have beneficial effects on health as antioxidant, antimicrobial, antihypertensive, anticancer etc. Enzymatic hydrolysis action can easily produce peptides during gastrointestinal digestion that can be facilitated by utilization of fermented dairy products like cheese, sour milk and yogurt. Milk related bioactive peptides are getting attention in context of commercial interest. On commercial scale, emerging techniques e.g. chromatography and membrane separation are applied in the production of milk derived bioactive peptides. In industries, to produce such ingredients, techniques like ultrafiltration and nanofiltration are also employed. Production of such type of peptides from high protein raw material can be uplifted to commercial level using controlled fermentation with LAB in bioreactor. In future, isolation of peptides from microbial strains recombined technology and production of explicit strains are likely to be employed.
生物活性肽;生理效益和商业应用
牛奶及其相关产品被认为是生物活性肽的丰富来源,具有作为营养保健食品成分的潜力。奶牛多肽在提高抗氧化效率中起着关键作用。这些健康促进成分具有抗氧化、抗菌、降压、抗癌等有益健康作用。酶水解作用在胃肠道消化过程中很容易产生多肽,利用发酵乳制品如奶酪、酸乳和酸奶可以促进多肽的产生。与牛奶相关的生物活性肽在商业上越来越受到关注。在商业规模上,色谱和膜分离等新兴技术被应用于乳源性生物活性肽的生产。在工业中,为了生产这些成分,还采用了超滤和纳滤等技术。以高蛋白原料为原料,利用生物反应器中的LAB控制发酵,可将此类多肽的生产提高到商业水平。在未来,从微生物菌株中分离肽重组技术和生产显式菌株可能被采用。
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