Primary Squamous Cell Carcinoma of the Renal Parenchyma: A Rare Case with Review of Literature

Abstract

Primary renal squamous cell carcinoma (SCC) is an extremely rare primary malignancy of the kidney withonly few cases that have been reported in the literature. The indolent course of the disease and the lack of specific clinical and radiological features may be re - sponsible of the delay in the diagnosis leading to an advanced stage of disease at diagnosis with poor outcomes. We present the case of a 65-year-old man with long standing renal stone disease and recurrent pyelonephritis in his history, admitted for management of locally advanced renal tumor with distant metastases where histology of biopsy revealed SCC. We report this case to underline the rarity of the renal location as primary site of squamous cell carcinoma, the clinic-radiological and histopathologic features, in addition to treatment management and prognosis.