Efficacy of Oral Toltrazuril in Newborn Piglet

Supaporn Somrup, Pitchayapa Saracharoen
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Abstract

Drug in piglets has a protective effect against dysentery. The aims of this study were determined the efficacy of toltrazuril in newborn-piglets. In 2 piglets of 819 piglets were divided into 2 groups. Baycox® drug group, using 446 piglets. Zurilguard® drug by using 373 piglets by adding a dose of toltrazuril antibiotic 1 ml. by oral suspension. It was found that the weaned weight of the Baycox® and Zurilguard® was found no significant difference (P > 0.05). The percentage of farrowing crate damage for the Baycox® of drugs had 10.23 % (39/407). In Zurilguard®, there was a percentage of farrowing crate damage at 3.18 % (14/359). As a result, percentages of farrowing crate damage were significantly different in both groups (P < 0.05). Efficacy from FCS indicated that Baycox® was more effective at returning piglets to diarrhea FCS 3 in newborn-piglets 39.24% (175/446) pigs at 7 day 43.64% (182/417) pigs at 14 day 24.27 % (100/412) weaned 25.80% (105/407). FCS indicated that Zurilguard® was more effective at returning piglets to FCS-3. In newborn-piglets 33.51% (125/373) piglets 7 days 37.82% (138/366) at piglets 14 days 58.96 % (214/363) weaned 42.82% (153/359). Zurilguard® had a lower rate of returning of FCS-3 in newborn-piglets and pig at 7 day than the Baycox® but rate of return of FCS-3 in pig at 14 day and weaned pigs more than Baycox®. In conclusion of oral toltrazuril that found efficacy of Zurilguard® for mortality rate of newborn-piglets to weaning in 21 days more than Baycox®. 
口服托曲祖利对新生仔猪的疗效
仔猪用药对痢疾有保护作用。本研究的目的是确定托曲祖利对新生仔猪的疗效。819头仔猪中2头分为2组。Baycox®药物组,使用446头仔猪。在373头仔猪中加入1 ml的托曲祖利抗生素口服混悬液。结果发现,Baycox®和Zurilguard®的断奶体重差异不显著(P > 0.05)。产箱破损率为10.23%(39/407)。在Zurilguard®中,分娩箱伤害百分比为3.18%(14/359)。结果表明,两组产仔箱损伤率差异有统计学意义(P < 0.05)。FCS的效果表明,在新生仔猪中,7日龄39.24%(175/446)、14日龄43.64%(182/417)、断奶25.80%(105/407)的仔猪中,Baycox®使仔猪恢复腹泻的效果更好。FCS表明,Zurilguard®使仔猪恢复到FCS-3更有效。初生仔猪33.51%(125/373),7日龄37.82%(138/366),14日龄58.96%(214/363),断奶42.82%(153/359)。与Baycox®相比,Zurilguard®在新生仔猪和仔猪7天时的FCS-3返回率较低,但在仔猪14天时和断奶仔猪中的FCS-3返回率高于Baycox®。综上所述,口服妥曲祖利发现Zurilguard®对新生仔猪21天至断奶死亡率的影响高于Baycox®。
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