DESIGN OF BICORPORAL PUMP FOR THE TREATMENT OF HYDROCEPHALUS

D. Cole, Shavonna Warren, Brian Kroeter, Michael E. Flatt, K. Nair, Martin J Morris, Julian Lin
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Abstract

With the current design for shunt systems used to treat hydrocephalus, tissue from the brain ventricle can cause blockages that obstruct cerebrospinal fluid (CSF) flow through the proximal catheter. Previous work demonstrated that the reversing of flow through the proximal catheter can restore flow through a blocked catheter. Periodic backwash through the proximal catheter can prevent obstructions and maintain adequate drainage. This project aims to design a pump that can periodically reverse the flow of CSF to backwash the proximal catheter. To reduce the complexity of the implanted components, a simple diaphragm pump can be externally actuated. Actuation of the pump can be achieved using an electromagnet located outside of the body; a metal cap placed on the diaphragm can be magnetically manipulated to pump CSF and backwash the proximal catheter. Testing demonstrates the feasibility of this pump design with an achieved flow rate of 3.4 to 4 mL/min. This bicorporal pump used as part of a backwashing system may favorably change the shunt failure rate and provide a more robust treatment for hydrocephalus.
治疗脑积水的双腔泵的设计
目前用于治疗脑积水的分流系统的设计,来自脑室的组织会造成阻塞,阻碍脑脊液(CSF)通过近端导管。先前的研究表明,通过近端导管的血流逆转可以恢复阻塞导管的血流。通过近端导管定期反冲洗可以防止阻塞并保持足够的引流。本项目旨在设计一种泵,可以周期性地逆转CSF的流动,以反冲洗近端导管。为了减少植入部件的复杂性,一个简单的隔膜泵可以外部驱动。所述泵的驱动可以使用位于所述本体外部的电磁铁来实现;放置在隔膜上的金属帽可通过磁力操纵泵入脑脊液并反冲洗近端导管。测试证明了这种泵设计的可行性,达到了3.4至4毫升/分钟的流量。作为反冲洗系统的一部分,这种双体泵可能有利于改变分流失败率,并为脑积水提供更有力的治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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