Cryotherapy of the distal limbs: an effective treatment for equine laminitis following onset of lameness?

Lucy Ryde
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引用次数: 1

Abstract

PICO question In horses with acute laminitis, does cryotherapy of the distal limbs applied after onset of clinical signs lead to improved clinical outcomes compared to horses treated without cryotherapy?   Clinical bottom line Category of research question Treatment The number and type of study designs reviewed Four papers were critically appraised; there were three randomised, controlled trials, and one retrospective cohort study. Strength of evidence Weak Outcomes reported There were reduced histological changes and lamellar injury in limbs treated with cryotherapy in the randomised controlled trials and reduced clinical severity of laminitis in horses treated with cryotherapy in the retrospective cohort study. Conclusion In horses with acute laminitis there is weak evidence to suggest that cryotherapy of the distal limbs is an effective treatment option when applied following onset of clinical signs. Further randomised, controlled trials should be performed to assess clinical outcomes of cryotherapy in order to draw definitive conclusions.   How to apply this evidence in practice The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources. Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.  
远端肢体冷冻疗法:一种有效的治疗马跛行后的足板炎的方法?
对于患有急性板膜炎的马,在出现临床症状后对远端肢体进行冷冻治疗,与未进行冷冻治疗的马相比,是否能改善临床结果?临床底线研究问题类别治疗研究设计审查的数量和类型4篇论文被严格评价;共有3项随机对照试验和1项回顾性队列研究。在随机对照试验中,接受冷冻治疗的四肢的组织学改变和板层损伤减少,在回顾性队列研究中,接受冷冻治疗的马的板层炎的临床严重程度降低。结论对于患有急性板膜炎的马,有微弱的证据表明,在出现临床症状后,对远端肢体进行冷冻治疗是一种有效的治疗选择。为了得出明确的结论,应该进行进一步的随机对照试验来评估冷冻疗法的临床结果。如何将证据应用于实践应考虑多种因素,不限于:个人临床专业知识、患者的情况和所有者的价值观、您工作的国家、地点或诊所、您面前的个案、治疗方法和资源的可用性。知识摘要是帮助加强或告知决策的资源。他们不会凌驾于从业者的责任或判断之上,去做对他们照顾的动物最好的事情。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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