MEMS based Chip for Blood Cell Sorting using Microfluidic Channel

Abstract

Hydraulic jump concept is used to separate and capture blood cells in this study. The two-dimensional microfluidic simulation model is used to create the devices. In many medical tests, physical features of cells of interest, such as size, deformability, and electric and magnetic properties, have become more important because of the inherent difficulties of isolation techniques based on biomarkers and antigens. In this study, cell/particle sorting in microchannels is investigated by using the inherent hydrodynamic effects. Microfluidic hydraulic jumps may be induced by turning high-speed flow in a microfluidic channel into a flow that has high potential energy by varying the channel height, much as in macrofluidics. Cells of varying sizes have their own chambers, such as those measuring 9 and 4 micrometres. The proposed microfluidic device can be used for sorting RBCs and WBCs from whole blood sample