Obstructive Sleep Apnea Classification Using Snore Sounds Based on Deep Learning

Apichada Sillaparaya, A. Bhatranand, Chudanat Sudthongkong, K. Chamnongthai, Y. Jiraraksopakun
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Abstract

Early screening for the Obstructive Sleep Apnea (OSA), especially the first grade of Apnea-Hypopnea Index (AHI), can reduce risk and improve the effectiveness of timely treatment. The current gold standard technique for OSA diagnosis is Polysomnography (PSG), but the technique must be performed in a specialized laboratory with an expert and requires many sensors attached to a patient. Hence, it is costly and may not be convenient for a self-test by the patient. The characteristic of snore sounds has recently been used to screen the OSA and more likely to identify the abnormality of breathing conditions. Therefore, this study proposes a deep learning model to classify the OSA based on snore sounds. The snore sound data of 5 OSA patients were selected from the opened-source PSG- Audio data by the Sleep Study Unit of the Sismanoglio-Amalia Fleming General Hospital of Athens [1]. 2,439 snoring and breathing-related sound segments were extracted and divided into 3 groups of 1,020 normal snore sounds, 1,185 apnea or hypopnea snore sounds, and 234 non-snore sounds. All sound segments were separated into 60% training, 20% validation, and 20% test sets, respectively. The mean of Mel-Frequency Cepstral Coefficients (MFCC) of a sound segment were computed as the feature inputs of the deep learning model. Three fully connected layers were used in this deep learning model to classify into three groups as (1) normal snore sounds, (2) abnormal (apnea or hypopnea) snore sounds, and (3) non-snore sounds. The result showed that the model was able to correctly classify 85.2459%. Therefore, the model is promising to use snore sounds for screening OSA.
基于深度学习的鼾声阻塞性睡眠呼吸暂停分类
早期筛查阻塞性睡眠呼吸暂停(OSA),特别是呼吸暂停-低通气指数(AHI)一级,可以降低风险,提高及时治疗的有效性。目前诊断阻塞性睡眠呼吸暂停的金标准技术是多导睡眠图(PSG),但该技术必须在专家的专业实验室中进行,并且需要在患者身上安装许多传感器。因此,它是昂贵的,可能不方便病人自检。鼾声的特征最近被用来筛查阻塞性睡眠呼吸暂停,更有可能识别呼吸条件的异常。因此,本研究提出了一种基于鼾声的深度学习模型对OSA进行分类。5例OSA患者的鼾声数据由雅典Sismanoglio-Amalia Fleming总医院睡眠研究组从开源的PSG- Audio数据中选取[1]。提取2439个与打鼾及呼吸相关的声音片段,分为3组,分别为1020个正常打鼾声、1185个呼吸暂停或低通气打鼾声和234个非打鼾声。所有声音片段分别被分成60%的训练集、20%的验证集和20%的测试集。计算一个声音片段的Mel-Frequency倒谱系数(MFCC)的平均值作为深度学习模型的特征输入。该深度学习模型使用了三个完全连接的层,将其分为三组:(1)正常打鼾声,(2)异常(呼吸暂停或呼吸不足)打鼾声和(3)非打鼾声。结果表明,该模型的分类正确率为85.2459%。因此,该模型有望利用鼾声筛查OSA。
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