Relationship between carotid atheroma thickness and albuminuria in diabetic patients

Dr.BASIM Audib Motar, Dr. Methaq A. M. Hussein, Dr. Oras Majeed
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Abstract

Our aim in this study to assess the efficacy of albuminuria in type 2 diabetes mellitus to be as predictor and independent marker of atherosclerosis by measurement of carotid intimal-medial thickness (CIMT) by high frequency ultrasonography. One hundred twenty participants in this study, 45 as a control healthy person and the others 75 patients with type 2 diabetes mellitus were included in this study. We divided into three groups: group 1 which is the control group, and group 2 those patients who are the diabetic without albuminuria, and group 3 are the diabetic patients with albuminuria. The intimal-medial thickness (IMT) was measured by high frequency ultrasonography. Other laboratory investigations were measured like HbA1c, fasting blood sugar, lipid profile. The intimal-medial thickness (IMT) was found higher in group 3 than group 1 and group 2 (P value < 0.05). In conclusion, there is a significant association between micro- albuminuria and IMT as a marker of atherosclerosis in type 2 diabetes mellitus.
糖尿病患者颈动脉粥样硬化厚度与蛋白尿的关系
本研究的目的是通过高频超声测量颈动脉内膜-内侧厚度(CIMT)来评估蛋白尿在2型糖尿病患者中作为动脉粥样硬化的预测和独立标志的作用。本研究共纳入120例受试者,其中45例为健康对照,75例为2型糖尿病患者。我们分为三组:第一组是对照组,第二组是没有蛋白尿的糖尿病患者,第三组是有蛋白尿的糖尿病患者。采用高频超声测量内膜-内侧厚度(IMT)。其他实验室调查如糖化血红蛋白、空腹血糖、血脂等。组3的内膜-内侧厚度(IMT)高于组1和组2 (P值< 0.05)。总之,微量白蛋白尿和IMT作为2型糖尿病动脉粥样硬化的标志物之间存在显著关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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