The Indonesian Central Nervous System Tumors Registry (Ina-CTR) : 7 years result from single institution of primary brain tumor epidemiology

Abstract

Background: Primary brain tumor is one of the most cases the neurosurgeon could found, despite good neurosurgery progress, still there is no epidemiologic data that collected from Indonesia as a low middle-income country in Asia. Objective: The Indonesian central nervous system tumors registry (Ina-CTR) aims to provide epidemiologic data on primary brain tumor in Indonesia and to provoke more wider data collection in Indonesia as a whole nation. Methods: We collect data from medical records retrospectively from all primary brain tumor patients that we operated in single centre, Dr. Soetomo general academic hospital, from 2012 to 2018. Data collected were gender, age, clinical manifestations, radiographic, operations, and histopathology. All patients underwent surgery for sampling whether biopsy, partial excision or total excision to obtain histopathological data. Results: A total of 1540 patients were diagnosed with primary brain tumors from 2012-2018. Brain tumors occurred in females more often than in males (female:male, 1.48:1). The most common tumor was meningioma 568 cases (36.9%). Gliomas 553 cases (35.9%), pituitary tumors 195 cases (12.7%), and nerve sheath tumors 92 cases (5.9%) followed in incidence. Glioblastomas accounted for 5.3% of all tumors and 41.8% of all gliomas. In children (<18 years), sellar region tumors (pituitary and craniopharyngioma), embryonal / primitive / medulloblastoma, and germ cell tumors were the most common tumors. Conclusion: This study should provide valuable information regarding the primary brain tumor epidemiology in Indonesia.