P80 Rebound in asthma exacerbations following relaxation of COVID-19 restrictions

F. Tydeman, A. Martineau, P. Pfeffer
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Abstract

P80 Figure 1Generalised additive models showing trends in behaviours and acute respiratory infections (ARI) from November 2020 to April 2022 in UK adults with asthma. A, visits to indoor public places. B, visits to other households. C, use of face coverings. D, RT-PCR or antigen test-confirmed COVID-19. E, ARI testing negative for SARS-CoV-2 by RT-PCR or antigen test. F, asthma exacerbations requiring treatment with systemic corticosteroids and/or hospitalisation. Dotted lines show 95% confidence intervals[Figure omitted. See PDF]ConclusionsRelaxation of COVID-19 restrictions coincided with decreased use of face coverings, increased social mixing and a rebound in ARI and asthma exacerbations. Associations between incident ARI and risk of exacerbation were similar for non-COVID ARI and COVID-19, both before and after emergence of the omicron variant of SARS-CoV-2.ReferenceThorax, 2021. 76(9): p. 867–873.Please refer to page A214 for declarations of interest related to this .
放宽COVID-19限制后哮喘加重的P80反弹
图1从2020年11月到2022年4月,英国成人哮喘患者的行为和急性呼吸道感染(ARI)趋势的广义加性模型。A、参观室内公共场所。B,拜访其他家庭。C、使用面罩。D、经RT-PCR或抗原检测确认的COVID-19。E,急性呼吸道感染经RT-PCR或抗原检测呈阴性。F,哮喘加重需要全身性皮质类固醇治疗和/或住院治疗。虚线表示95%置信区间[图略]。结论放宽COVID-19限制与口罩使用减少、社交交往增加以及急性呼吸道感染和哮喘加重的反弹同时发生。在SARS-CoV-2组粒变异出现之前和之后,非COVID-19型ARI和COVID-19的急性呼吸道感染与急性加重风险之间的关联相似。ReferenceThorax, 2021年。76(9): p. 867-873。有关的利益声明,请参阅A214页。
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