New drug targets and new approaches for Hepatitis B virus theraphy

Abstract

Hepatitis B virus (HBV) therapy is still a topic of discussion. Because of that approved agents for HBV have some disadvantages, there is a need for new treatment targets and approaches for HBV. New treatment targets for HBV consist revers transcription, immunoregulation, cccDNA formation and regulation, maturation and secretion of infectious virions and subviral particules, viral receptor, entry and cytosolic transport, nucleocapsid assembly. Therapeutic vaccination and traditional Chinese medicine are the other options for novel agents for HBV treatment.