Fermentative Production of MCL Poly(3-hydroxyalkanoate)

Abstract

Introduction Historical Outline Occurrence Functions Biochemistry β-Oxidation Fatty Acid Synthesis Unsaturated Fatty Acids Physiology and Process Development Fermentation Process Development Control of MCL-Poly(3HA) Monomer Composition Oxygen Transfer and Heat Production Byproducts Molecular Genetics Recombinant Pseudomonads Recombinant E. coli Downstream Processing Production MCL-Poly(3HA) Production versus SCL-Poly(3HA) Production Producers Applications Patents Outlook and Perspectives Acknowledgements Keywords: medium-chain-length poly(3-hydroxyalkanoate); polyester; fermentation; fluorescent Pseudomonads; Pseudomonas oleovorans; Pseudomonas putida; MCL-Poly(3HA) synthesis; fatty acid synthesis; β-oxidation; genetic modification; Escherichia coli; continuous cultivation; fed-batch cultivation; two-phase cultivation; oxygen transfer; heat transfer; down-stream processing