MYELOID SARCOMA, A RARITY OF THE HEAD AND NECK REGION - A CASE REPORT

M. Krishnamoorthy, Bee Sun Lee, Sellymiah Adzman, S. Hitam
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Abstract

Myeloid sarcoma is a rare disease, where a mass (tumour) of either myeloblasts or immature myeloid cells conglomerate in extramedullary anatomic sites. It may arise de-novo or it may present in association with acute myeloid leukemia. It can also occur in patients with myelodysplastic syndromes, myeloproliferative disorders, and as blast transformation in myeloproliferative neoplasia. Myeloid sarcoma of the head and neck area can pose a diagnostic challenge because of the low frequency of occurrence, and the vast diversity of tumours occurring from multiple lineages in this anatomic region. This can lead to a broad spectrum of various differential diagnoses. Therefore, a high index of suspicion is required when dealing with a possible case of myeloid sarcoma, as it is a time sensitive diagnosis with various diagnostic dilemmas. Here , we report an example, a case of tonsillar myeloid sarcoma. We wish to highlight the investigations that helped us procure this diagnosis in a timely manner.
髓样肉瘤,罕见的头颈部- 1例报告
髓样肉瘤是一种罕见的疾病,髓外解剖部位出现成髓细胞或未成熟髓样细胞团块(肿瘤)。它可能从头出现,也可能与急性髓性白血病有关。它也可以发生在骨髓增生异常综合征、骨髓增生性疾病和骨髓增生性肿瘤的原细胞转化患者中。头颈部的髓系肉瘤由于发病率低,且该解剖区域的肿瘤来自多个谱系,具有很大的多样性,因此对诊断具有挑战性。这可能导致各种各样的鉴别诊断。因此,在处理可能的髓系肉瘤病例时,需要高度的怀疑指数,因为它是一个具有各种诊断困境的时间敏感诊断。在此,我们报告一例扁桃体髓样肉瘤。我们希望强调帮助我们及时获得这一诊断的调查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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