Redo surgery in failed fundoplication in patients with gastroesophageal reflux disease

Serghei Cumpata, V. Guzun, Vladimir Iacub, E. Gutu
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Abstract

Redo surgery in failed fundoplication in patients with gastroesophageal reflux disease. Background. Laparoscopic antireflux surgery is a frequently performed procedure for the treatment of refractory gastroesophageal reflux in surgical clinics, with excellent and good symptomatic results in 90% to 95% of cases. Despite a high rate of success, the failure of laparoscopic fundoplication occurs in 2-17% of cases. When some patients can be treated conservatively, in approximately 3% to 6% cases the revision surgery is required due to recalcitrant and recurrent symptoms or appearance of complications. Methods. From 2011 to 2019, revision surgery was performed on 10 patients (all women) between the ages of 18 and 63 years. Patient demographics, primary and repeat surgery techniques, preoperative symptoms, anatomical pattern of failure, perioperative morbidity, operative complications, conversion rate, length of hospital stay, immediate and distant results were evaluated. Results. The first surgical procedure was laparoscopic Nissen-Rossetti fundoplication in 9 patients and Dor – in 1 patient. The types of fundoplication failure were: transhiatal wrap migration - 6 cases, „slipped” Nissen – 1 and paraesophageal hernia – 3. Eight patients were operated laparoscopically with the conversion rate of 50% (4 cases) – caused by dense adhesions – 3 cases, and perforation of gastric fundus – 1. Nissen fundoplication was redone in 4, converted to Toupet – in 3, newly formed after Dor fundoplication – in 1 and was left in place – in 2 patients. In all cases the repeated cruroplasty was performed, and in 3 cases - reinforcement with Gore-Tex patches. Laparoscopy operating room time was 146±54 minutes (from 95 to 240 minutes). Intraoperative complication occurred in one patient – gastric perforation. Length of hospital stay was 5 days for laparoscopic, 8 days for converted. Follow-up from 4 to 9 years: all patients without reflux symptoms, 1 – mild bloating, 2 – mild dysphagia without hernia and reflux recurrence. Conclusions. The redo surgery it is a more complex intervention, with higher technical requirements than primary one and is associated with a high rate of conversion and intraoperative complications. However, redo surgery can be carried out efficiently and safely by an experienced surgical team in dedicated centers.
胃食管反流病患者复底失败的再手术治疗
胃食管反流病患者复底失败的再手术治疗。背景。腹腔镜抗反流手术是外科诊所治疗难治性胃食管反流的常用方法,90% ~ 95%的病例症状效果优异。尽管成功率很高,但2-17%的病例发生腹腔镜下盆底复制失败。当一些患者可以保守治疗时,约3%至6%的病例由于顽固性和复发性症状或并发症的出现而需要翻修手术。方法。从2011年到2019年,对10名年龄在18岁至63岁之间的患者(均为女性)进行了翻修手术。评估患者人口统计学、初次和重复手术技术、术前症状、失败的解剖模式、围手术期发病率、手术并发症、转换率、住院时间、近期和远期结果。结果。第一次手术是腹腔镜下Nissen-Rossetti底折叠,9例,Dor - in 1例。手术失败类型为:经膈膜移位6例,滑移型尼森1例,食管旁疝3例。腹腔镜下手术8例,转化率50%(4例),其中粘连致密3例,胃底穿孔1例。4例患者重新进行了Nissen底复制,3例患者转为Toupet底复制,1例患者在Dor底复制后重新形成,2例患者保留原位。所有病例均行重复成形术,其中3例用Gore-Tex补片加固。腹腔镜手术时间为146±54分钟(95 ~ 240分钟)。术中并发症1例,胃穿孔。腹腔镜组住院时间5天,转换组住院时间8天。随访4 ~ 9年:所有患者无反流症状,1例轻度腹胀,2例轻度吞咽困难,无疝和反流复发。结论。重做手术是一种更复杂的干预,比初次手术有更高的技术要求,并且有较高的转换率和术中并发症。然而,重做手术可以在专门的中心由经验丰富的外科团队高效安全地进行。
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