Salivary IgA and Dental Caries in Type II Diabetics in Indian Adult Population

Abstract

Aim: To evaluate relationship between Salivary IgA and Dental caries in Type II Diabetics in Indian Adult Population. Method: Study was conducted on 30 patients of age group ranging from 25-60years including type II diabetic and non diabetic patients. Patients were divided into 3 groups of 10 subjects each according to diabetic and DMFT scores as G-1 (control, non diabetic) DMFT- 0, G-2 (non diabetic) DMFT 4 - 8 and G-3 (diabetic) DMFT 4 - 8. Unstimulated saliva samples were collected from each subject for estimation of IgA using the Turbidometric method. Data obtained were statistically analysed. Results: Correlation of Salivary IgA and DMFT showed steady decrease in values of Salivary-IgA from Group I – III. The variation in Salivary- IgA level was Very Highly Significant [VHS] when diabetic DMFT 4-8 was compared with control and non diabetic DMFT 4-8; Highly significant [HS] between control and non diabetic DMFT 4-8. Conclusion: Salivary-IgA values showed an inverse relationship to the DMFT values with levels of Salivary-IgA decreasing with an increase in DMFT Values. Salivary-IgA level in type II Diabetic patients with DMFT-4-8 had significantly lower values than non diabetic patients of similar DMFT scores.