The relation of the clinical picture to the histopathology of snuff dipper"s lesions in a Swedish population.

Journal of oral pathology Pub Date : 1976-07-01
T Axéll, H Mörnstad, B Sundström
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Abstract

The relation of the clinical picture of snuff dipper's lesions to the histopathological appearance was studied in 114 male dippers aged 20-88 years. Histological study revealed increased epithelial thickness, a vacuolated surface layer with wavelike, eosinophilic spikes directed toward the surface having a narrow, eosinophilic band as a demarcation toward the prickle cell layer, acanthosis, and a slight inflammatory reaction. Thirteen cases showed an increased number of eosinophilic granulocytes, and nine cases contained amorphous, weakly eosinophilic areas in the connective tissue papillae. No epithelial dysplasia was observed. Increased epithelial thicknees, especially the presence of a vacuolated surface layer, was the only histologic feature that could be correlated with the severity of clinical appearance of the lesions. Deeply located changes, like inflammation and amorphous areas, however, were not reflected in the clinical grading of the lesions.

瑞典人鼻烟壶病变的临床表现与组织病理学的关系。
我们对 114 名年龄在 20-88 岁之间的男性鼻烟壶使用者进行了鼻烟壶病变的临床表现与组织病理学外观之间关系的研究。组织学研究显示,上皮厚度增加,表层空泡化,表面有波浪状的嗜酸性尖峰,以一条狭窄的嗜酸性带作为刺细胞层的分界线,棘层增生,以及轻微的炎症反应。13 个病例显示嗜酸性粒细胞数量增加,9 个病例的结缔组织乳头中含有无定形的弱嗜酸性区域。未观察到上皮发育不良。上皮增厚,尤其是出现空泡化表层,是唯一能与病变临床表现的严重程度相关联的组织学特征。然而,炎症和无定形区等深层病变并没有反映在病变的临床分级中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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