Protein analyses in myelomatosis.

Abstract

The criteria for the admission of patients to the Medical Research Council's (MRC) myeloma trials are the finding of abnormal plasma cells in bone marrow films or sections and in addition either of characteristic skeletal lesions demonstrated radio-logically or of characteristic protein changes in the serum or urine. Ninety per cent of the patients in the first myeloma trial satisfied all three criteria (Medical Research Council, 1971).